All news with #biosecurity tag

The AI Fix #77: Genome LLM, Ethics, Robots and Romance

🔬 In episode 77 of The AI Fix, Graham Cluley and Mark Stockley survey a week of unsettling and sometimes absurd AI stories. They discuss a bioRxiv preprint showing a genome-trained LLM generating novel bacteriophage sequences, debates over whether AI should be allowed to decide life-or-death outcomes, and a woman who legally ‘wed’ a ChatGPT persona she named "Klaus." The episode also covers a robot's public face-plant in Russia, MIT quietly retracting a flawed cybersecurity paper, and reflections on how early AI efforts were cobbled together.

AI-Designed Bioweapons: The Detection vs Creation Arms Race

🧬 Researchers used open-source AI to design variants of ricin and other toxic proteins, then converted those designs into DNA sequences and submitted them to commercial DNA-order screening tools. From 72 toxins and three AI packages they generated roughly 75,000 designs and found wide variation in how four screening programs flagged potential threats. Three of the packages were patched and improved after the test, but many AI-designed variants—often likely non-functional because of misfolding—exposed gaps in detection. The authors warn this imbalance could produce an arms race where design outpaces reliable screening.