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Tue, October 21, 2025

Critical MinKNOW Vulnerabilities Allow Remote Access and DoS

⚠️ Oxford Nanopore Technologies MinKNOW sequencing software contains multiple remotely exploitable vulnerabilities (highest CVSS v4 8.3) that can permit unauthorized access, data manipulation, and denial-of-service on affected devices. Attackers can discover devices via network scanning, exploit authentication that trusts host IPs, and reuse tokens stored in world-readable temporary files to gain persistent access or redirect sequencing output. Oxford Nanopore advises upgrading to versions later than 24.11; CISA recommends minimizing network exposure, isolating control networks, and using secure remote access methods while applying other mitigations.

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